Related Experiment Video
Updated: Sep 10, 2025

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
Published on: May 4, 2021
A Rare Case of Pneumomediastinum and Subcutaneous Emphysema Secondary to Recreational Nitrous Oxide Inhalation
Nicole C Oparaugo1, Jay Cadavona2, Sean D Delshad2
1Internal Medicine, University of California, Irvine, Irvine, USA.
Abstract:
The recreational inhalation of nitrous oxide, also known as laughing gas, continues to rise due to its euphoric effects and easy accessibility. Clinicians may therefore encounter patients suffering from the potential adverse effects of nitrous oxide inhalation more commonly. We present a case of a 35-year-old man who presented with neck and facial swelling and pleuritic chest pain after a two-day recreational binge of nitrous oxide inhalation. The patient was found to have subcutaneous emphysema and pneumomediastinum, rare adverse effects of nitrous oxide inhalation. The patient's symptoms improved with supportive care.
More Related Videos
02:09Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
05:43Topical Airway Anesthesia for Awake-endoscopic Intubation Using the Spray-as-you-go Technique with High Oxygen Flow
Published on: January 13, 2017
Related Concept Videos
Pneumothorax-II
Clinical Manifestations:
Pneumothorax-I
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pulmonary Cycle: Exhalation
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Acute Respiratory Failure-II
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Acute Respiratory Failure-III