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Cardiac Complications in Cancer Patients Following Chemotherapy and Radiotherapy
Md Zillur Rahman Bhuiyan1, Harisul Hoque2, Sarwar Alam1
1Department of Clinical Oncology, Bangladesh Medical University, Dhaka, BGD.
Cureus
|August 21, 2025
Summary
Cancer treatments like chemotherapy and radiotherapy significantly increase cardiac risks in patients. This study found a high prevalence of cardiac complications, including hypertension and diabetes, highlighting the need for integrated cardiac care in Bangladesh.
Area of Science:
- Cardiology
- Oncology
- Public Health
Background:
- Chemotherapy and radiotherapy pose significant risks to cardiovascular health in cancer patients.
- Potential complications include cardiomyopathy, arrhythmias, and coronary artery disease.
Purpose of the Study:
- To investigate the prevalence and nature of cardiac complications in Bangladeshi cancer patients.
- Focus on patients receiving chemotherapy, radiotherapy, or both.
Main Methods:
- Prospective cross-sectional observational study conducted in Dhaka, Bangladesh (April 2023 - May 2024).
- 339 cancer patients (age >18) evaluated for cardiac complications using clinical assessments, ECG, ECHO, and biomarkers.
- Data analyzed using SPSS Statistics, with P < 0.05 considered statistically significant.
Main Results:
- Mean participant age was 52.4 years.
- Significant increases in hypertension (24.5%) and diabetes (20.6%) post-treatment.
- Elevated cardiac biomarkers (Troponin-I, NT-proBNP, CK-MB) indicated heightened cardiac risk (P < 0.001).
Conclusions:
- Substantial burden of cardiac complications observed in cancer patients undergoing chemotherapy/radiotherapy in Bangladesh.
- Emphasizes the need for integrated oncology and cardiac care for monitoring and management.
- Further research is needed for targeted interventions in the Bangladeshi population.
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