Related Experiment Video
Updated: May 5, 2026

Determining Genetic Expression Profiles in C. elegans Using Microarray and Real-time PCR
Published on: July 30, 2011
RMD-3 and RMD-6 identified as new components of the MSP fibrous body complex in C. elegans spermatocytes
Nirvanjyoti Sharma Shimul1, Elena B Benson1, Jake P Diaz1
1Biology, William & Mary, Williamsburg, Virginia, United States.
None:
The RMD (regulator of microtubule dynamics) protein family is conserved across various species but their activity and role in spermatogenesis is largely unexplored. Here we report developing an antibody against the two nearly identical proteins C. elegans RMD-3 and RMD-6 . This antibody detects RMD-3 /6 in both immunocytology and western blots. RMD-3 /6 colocalizes with the major sperm protein MSP to the fibrous bodies of spermatocytes, cytoplasm of spermatids, and pseudopods of spermatozoa. RMD-3 /6 are sperm-specific, yet male fertility in triple rmd-2 / rmd-3 / rmd-6 knockout mutants is unaffected under conditions tested.
More Related Videos
Related Concept Videos
Spermatogenesis
Spermatogenesis
The process of spermatogenesis can be divided into mitosis, meiosis, and spermiogenesis. During mitosis, the spermatogonia or stem cells divide to produce two identical daughter cells, type A and B spermatogonia. Type-A...

