Defocus correction and noise reduction using a hybrid ptychography and Centre-of-Mass algorithm

Zhiyuan Ding1, Chen Huang2, Adrián Pedrazo-Tardajos2

  • 1Department of Materials, University of Oxford, Oxford, UK.

Journal of Microscopy
|August 21, 2025
PubMed
Summary

A new method, Side Band masked Centre-of-Mass (SBm-COM) and integrated Centre-of-Mass (SBm-iCOM), enhances phase-contrast imaging in 4D Scanning Transmission Electron Microscopy (STEM). This technique reduces noise and compensates for aberrations, improving imaging for challenging samples.