Vitamin E deficiency associated with vision loss and bulbar weakness

Area of Science:

• Neurology
• Hepatology
• Nutritional Science

Background:

• Chronic cholestatic liver disease can lead to fat-soluble vitamin deficiencies.
• Vitamin E deficiency is a known cause of neurological impairment.

Observation:

• A 14-year-old boy presented with severe neurological deficits, including bulbar weakness and vision loss.
• These symptoms were attributed to prolonged and severe vitamin E deficiency.

Findings:

• The patient exhibited neurological symptoms beyond typical vitamin E deficiency deficits.
• Severe bulbar weakness and vision loss were prominent features.
• Vitamin A deficiency might have also contributed to visual disturbances.

Implications:

• This case highlights the severe neurological and visual consequences of untreated vitamin E deficiency.
• Prompt identification and management of vitamin E deficiency are crucial for preventing irreversible damage.
• Early intervention can lead to the successful treatment of associated neurological and visual disorders.