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Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
Published on: June 23, 2015
Reversed cortico-medullary differentiation in kidneys on fetal magnetic resonance imaging - a case series
Monika Bekiesinska-Figatowska1, Jaroslaw Madzik2, Marcin Ring2
1Department of Diagnostic Imaging, Institute of Mother and Child, Ul. Kasprzaka 17a, Warsaw, 01-211, Poland. monika.bekiesinska@imid.med.pl.
Abstract:
The reversed cortico‑medullary differentiation in fetal kidneys on ultrasound has been described in the literature, but there have been no descriptions of such a finding on fetal magnetic resonance imaging (MRI) so far. The authors present three unrelated fetuses with hyperechoic kidneys on ultrasound (US) and reversed signal intensity of their cortex and pyramids on SSFSE/T2WI and FIESTA images on magnetic resonance imaging (MRI). All of them shared the same deletion of the long arm of chromosome 17 in the 17q12 region, responsible for the expression of clinical features of renal cysts and diabetes (RCAD) syndrome. All of them had multiple tiny kidney cysts on US after birth. This specific finding on fetal MRI may point at this specific genetic condition.
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