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Peripheral Artery Disease III: Interprofessional Care

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Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

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Peripheral Artery Disease I: Introduction

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Related Experiment Video

Updated: Sep 10, 2025

Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity

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Published on: January 31, 2025

A Novel Diabetic Limb Preservation Initiative.

¹*Clinical Professor, Podiatric Surgery, Department of Diabetes, Endocrinology and Metabolism Department of Oncologic Surgery, City of Hope National Comprehensive Cancer Center Duarte, CA. Diplomate, American Board of Foot and Ankle Surgery; Diplomate, American Board of Podiatric Medicine.

Journal of the American Podiatric Medical Association

|August 21, 2025

Summary

Integrating patient education on diabetic foot symptoms with podiatric care significantly reduced diabetic foot ulcers (DFUs) and amputations in cancer patients with diabetes. This approach enhances patient engagement and early detection of complications.

Keywords:

Health disparities diabetes and cancer diabetic foot ulcers patient education

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Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits

Preclinical Model of Hind Limb Ischemia in Diabetic Rabbits

Published on: June 2, 2019

Area of Science:

Oncology
Endocrinology
Podiatry

Background:

Diabetic foot ulcers (DFUs) and amputations are significant causes of morbidity and mortality in diabetic patients.
Cancer patients with diabetes face compounded risks due to immunosuppression, neuropathy, and vascular issues.
Foot complications in this population can lead to cancer therapy suspension, posing life-threatening risks.

Purpose of the Study:

To evaluate the impact of integrating symptom-focused patient education with coordinated podiatric care.
To reduce the incidence of DFUs and lower extremity amputations in diabetic cancer patients.
To assess the effectiveness of the Novel Limb Preservation Initiative model.

Main Methods:

A five-year retrospective review at an NCI-designated cancer center.
Inclusion of patients with Type II diabetes undergoing treatment for various cancers.
Targeted educational modules based on self-reported symptoms and individualized podiatric care with routine examinations and monitoring.

Main Results:

Achieved a DFU incidence of 2.8% and an amputation rate of 0.43%, below national benchmarks.
Demonstrated enhanced patient engagement through symptom-focused education.
Facilitated earlier detection of foot complications, including seemingly minor issues.

Conclusions:

Integrating diabetic foot symptom education with proactive podiatric monitoring significantly reduces DFUs and amputations.
The Novel Limb Preservation Initiative model is a scalable strategy for high-risk populations.
The model shows promise for broader implementation in diverse, underserved communities.