[What the e-MUST Registry Reveals About Myocardial Infarction in Women]
Frédéric Lapostolle1, Hakim Benamer2, Aurélie Loyeau3
1SAMU 93 (local emergency medical service), UF Recherche-Enseignement-Qualité, (Research, teaching and quality training unit) Avicenne Hospital - Public hospitals of Paris, Bobigny, France; Université Paris 13, INSERM Unit 942, Sorbonne Paris Cité, Bobigny, France.
Annales De Cardiologie Et D'Angeiologie
|August 21, 2025
Summary
Women with acute myocardial infarction (AMI) face higher mortality and younger onset ages than men. Targeted, gender-specific emergency care protocols are crucial for improving outcomes in female AMI patients.
Area of Science:
- Cardiology
- Emergency Medicine
- Gender Studies in Medicine
Context:
- Gender disparities in acute myocardial infarction (AMI) outcomes have been recognized for over 25 years.
- Women with AMI historically exhibit higher mortality rates compared to men.
- The e-MUST registry provides extensive data on ST-segment elevation myocardial infarction (STEMI) managed by Mobile Emergency and Resuscitation Services (SMUR).
Purpose:
- To analyze gender-specific differences in AMI presentation, management, and outcomes using the e-MUST registry.
- To investigate factors contributing to higher mortality in women with AMI.
- To identify potential gender biases in prehospital emergency medical services and inform targeted interventions.
Summary:
- Women with AMI experience higher mortality (OR=1.4) and a younger age of onset compared to men.
- A significant proportion of nonagenarian AMI patients are women, with improved outcomes linked to increased reperfusion rates.
- AMI in women often presents with nontraditional risk factors, circadian variations, and delayed emergency calls, alongside potential gender bias in medical dispatch decisions.
Impact:
- Highlights the need for heightened awareness and gender-specific training in emergency care for AMI.
- Underscores the necessity of tailored protocols to address unique challenges faced by women with AMI.
- Findings can guide the development of more equitable and effective prehospital management strategies for acute myocardial infarction.
Keywords:
Acute coronary syndromeEmergencyGenderGenrePrehsopitalPréhospitalierSamuSyndrome coronaire aigu ST+UrgenceMore Related Videos
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