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The effect of anti-nausea wristbands and STW-5 in children suffering from dyspepsia - a randomized double-blind
Corinne Légeret1, Sebastian Ludyga2, Muriel D'Aujourdhui3
1Pediatric Gastroenterology, University Childrens Hospital Basel, Basel, Switzerland.
Insights
Plant extract STW-5 and acupressure wristbands effectively treated functional dyspepsia (FD) in children. STW-5 showed a 68% symptom improvement, offering a cost-effective treatment option for pediatric FD.
Area of Science:
- Pediatric Gastroenterology
- Complementary and Alternative Medicine
Background:
- Functional dyspepsia (FD) is a prevalent condition in children, characterized by epigastric discomfort without identifiable structural or biochemical causes.
- The exact pathophysiology of pediatric FD remains unclear, leading to a lack of established treatment guidelines.
- This study addresses the need for effective and accessible therapeutic options for children with FD.
Purpose of the Study:
- To compare the therapeutic efficacy of a herbal preparation (STW-5) and acupressure wristbands in managing functional dyspepsia in pediatric patients.
- To evaluate the impact of these interventions on quality of life and symptom severity in children with FD.
Main Methods:
- A randomized, double-blind, placebo-controlled trial was conducted over four weeks.
- Participants completed validated questionnaires and visual analog scales (VAS) to assess quality of life and discomfort levels before and after the intervention.
- The study included 33 children (12 male, 21 female) aged 7-17 years.
Main Results:
- Significant symptom improvement was observed in most treatment groups after four weeks.
- Children receiving STW-5 experienced a 68% improvement in symptoms.
- Acupressure wristband (WB) and wristband-placebo (WBPL) groups showed 40% and 35% symptom improvement, respectively.
- A STW-5 placebo group exhibited an increase in symptoms, suggesting the efficacy of STW-5.
Conclusions:
- The herbal preparation STW-5 and anti-nausea wristbands represent a cost-effective and efficient therapeutic strategy for pediatric functional dyspepsia.
- This pilot study provides evidence supporting the use of STW-5 and acupressure as viable treatment options for children and adolescents with FD.
Background:
Functional dyspepsia (FD) is common in children and refers to discomfort in the epigastric/duodenal region, which cannot be explained by structural or biochemical abnormalities. Since the pathophysiology is still not fully understood, no guidelines in terms of treatment do exist.
Aim:
The aim of this study was to compare the therapeutical effect of plant extracts (STW-5) and acupressure in children with functional dyspepsia.
Methods:
This is a randomized, double-blind placebo-controlled trial. Before and after the allocated intervention of four weeks, participants had to fill in a cross-cultural validated questionnaire consisting of 52 questions to assess quality of life, as well as the extent of their discomfort (using a standardized visual analog scale (VAS)).
Results:
33 patients were included in the study: 12 male and 21 female with an average age of 12.09 years (range: 7-17 years). Symptoms improved after four weeks of intervention in most treatment-groups: By 68% in children, who received STW-5, by 40% in the wristband (WB)- group and by 35% in the wrist-band-Placebo-group (WBPL). Patients receiving STW-5- Placebo showed even an increase of symptoms.
Discussion:
This double-blind, placebo-controlled pilot study showed, that STW-5 and/or anti-nausea wristbands are a cheap and effective option to treat children and teenagers suffering from functional dyspepsia.
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