The effect of anti-nausea wristbands and STW-5 in children suffering from dyspepsia - a randomized double-blind

Corinne Légeret1, Sebastian Ludyga2, Muriel D'Aujourdhui3

  • 1Pediatric Gastroenterology, University Childrens Hospital Basel, Basel, Switzerland.

Klinische Padiatrie
|August 21, 2025
PubMed

Insights

Plant extract STW-5 and acupressure wristbands effectively treated functional dyspepsia (FD) in children. STW-5 showed a 68% symptom improvement, offering a cost-effective treatment option for pediatric FD.

Area of Science:

  • Pediatric Gastroenterology
  • Complementary and Alternative Medicine

Background:

  • Functional dyspepsia (FD) is a prevalent condition in children, characterized by epigastric discomfort without identifiable structural or biochemical causes.
  • The exact pathophysiology of pediatric FD remains unclear, leading to a lack of established treatment guidelines.
  • This study addresses the need for effective and accessible therapeutic options for children with FD.

Purpose of the Study:

  • To compare the therapeutic efficacy of a herbal preparation (STW-5) and acupressure wristbands in managing functional dyspepsia in pediatric patients.
  • To evaluate the impact of these interventions on quality of life and symptom severity in children with FD.

Main Methods:

  • A randomized, double-blind, placebo-controlled trial was conducted over four weeks.
  • Participants completed validated questionnaires and visual analog scales (VAS) to assess quality of life and discomfort levels before and after the intervention.
  • The study included 33 children (12 male, 21 female) aged 7-17 years.

Main Results:

  • Significant symptom improvement was observed in most treatment groups after four weeks.
  • Children receiving STW-5 experienced a 68% improvement in symptoms.
  • Acupressure wristband (WB) and wristband-placebo (WBPL) groups showed 40% and 35% symptom improvement, respectively.
  • A STW-5 placebo group exhibited an increase in symptoms, suggesting the efficacy of STW-5.

Conclusions:

  • The herbal preparation STW-5 and anti-nausea wristbands represent a cost-effective and efficient therapeutic strategy for pediatric functional dyspepsia.
  • This pilot study provides evidence supporting the use of STW-5 and acupressure as viable treatment options for children and adolescents with FD.
Abstract

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