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Updated: Aug 18, 2026

Habituation and Prepulse Inhibition of Acoustic Startle in Rodents
Published on: September 1, 2011
Interaction between consecutive learnings: inhibitory avoidance and habituation
Abstract:
Rats were submitted to step-down inhibitory avoidance training and to habituation of a rearing response to a tone with a 2-h interval between the two tasks, and were tested for retention of both tasks on the next day. When animals were trained first in inhibitory avoidance and then in habituation, retention of the avoidance behavior was impaired. When the animals were trained first in the habituation task and then in the avoidance task, retention of the two tasks was normal. The same results were obtained regardless of the order in which the two tasks were presented on the day of testing. This asymmetrical influence of habituation training on inhibitory avoidance retention could be due either to cognitive or, more likely, to task-specific neurochemical interactions.
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