Related Experiment Video
Updated: Sep 10, 2025

Basics of Multivariate Analysis in Neuroimaging Data
Published on: July 24, 2010
Identifiability and convergence behavior for Markov chain Monte Carlo using multivariate probit models
1Department of Mathematical Sciences, Michigan Technological University, Houghton, MI, USA.
None:
Multivariate probit models have been popularly utilized to analysis multivariate ordinal data. However, the identifiable multivariate probit models entail the covariance matrix for the underlying multivariate normal variables to be a correlation matrix, which brings a rigorous task to conduct efficient statistical analysis. Parameter expansion to make the identifiable model to be non-identifiable has been inevitably explored. However, the effect of the expanded parameters on the convergence of Markov chain Monte Carlo (MCMC) is seldomly investigated; in addition, the comparison of MCMC developed based on the identifiable model and that based on the non-identifiable model is hardly ever explored, especially for data with large sample sizes. In this paper, we conduct a thorough investigation to illustrate the effect of the expanded parameters on the convergence of MCMC and compare the behavior of MCMC between the identifiable and non-identifiable models. Our investigation provides a practical guide regarding the construction of non-identifiable models and development of corresponding MCMC sampling methods. We conduct our investigation using simulation studies and present an application using data from the Russia Longitudinal Monitoring Survey-Higher School of Economics (RLMS-HSE) study.
Related Concept Videos
Multicompartment Models: Overview
These models offer a more comprehensive representation of drug behavior in the body than one-compartment models. They accommodate the complexity of drug distribution,...
Mechanistic Models: Compartment Models in Individual and Population Analysis
Multi-input and Multi-variable systems
In the absence...
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation
On...
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...

