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Large Basal Cell Carcinoma Treated with Combination Topical Therapy
Kabir Al-Tariq1, Rama Abdin2, Naiem T Issa3
1Mr. Al-Tariq is with the Georgetown University School of Medicine in Washington, District of Columbia.
The Journal of Clinical and Aesthetic Dermatology
|August 22, 2025
Summary
Basal cell carcinoma (BCC), the most common skin cancer, can be treated with topical therapies. This case study explores a combination topical treatment for a large nodular BCC in an elderly patient.
Area of Science:
- Dermatology
- Oncology
Background:
- Basal cell carcinoma (BCC) is the most prevalent form of skin cancer in the United States.
- Standard treatments for BCC vary by size, grade, and subtype, including topical therapies, destructive methods, and surgical excision.
- Surgical intervention, while effective, is not always a viable option for all patients.
Observation:
- This case report details a novel combination topical treatment approach.
- The treatment was applied to a large nodular basal cell carcinoma.
- The patient was elderly and the BCC was located in a challenging inguinal region.
Findings:
- The study presents a case of successful management of a large nodular BCC.
- A combination topical therapy was utilized as an alternative to surgery.
- This approach was applied to an elderly patient with a BCC in a difficult-to-treat area.
Implications:
- Physicians should consider alternative, less invasive treatments for BCC when surgery is not feasible.
- Combination topical therapy may offer a viable option for managing complex BCC cases.
- This approach could improve treatment accessibility and patient outcomes for BCC, particularly in challenging locations or for elderly individuals.
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