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Risk of cancer and conventional syntethic DMARDS: A narrative review
Thelma Skare1, Jozélio Freire de Carvalho2
1Department of Rheumatology, Hospital Evangélico Mackenzie, Curitiba, PR, Brazil.
None:
Immunosuppressors and immunomodulators are widely used for the treatment of rheumatic diseases. Among them are the conventional Disease-Modifying Antirheumatic Drugs (DMARDs) such as methotrexate, azathioprine, antimalarials, cyclosporine, etc. These drugs can induce remission or control inflammation, improving patients' outcomes. Nevertheless, there is some concern that these drugs may have a carcinogenic potential, favoring the appearance of tumors. Herein, a narrative review of malignancy risk after using conventional DMARDs is done.
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