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Updated: Sep 10, 2025

Comparative Lesions Analysis Through a Targeted Sequencing Approach
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The JAK/STAT conundrum with mutational heterogeneity, immune defects, and the emergence of targeted therapies

Durmus Burak Demirkaya1,2,3, Burkay Cagan Colak1,2,3, Asena Pinar Sefer4

  • 1Division of Pediatric Allergy and Immunology, Faculty of Medicine, Marmara University, Istanbul, Türkiye.

Expert Review of Clinical Immunology
|August 22, 2025
PubMed
Abstract

Keywords:
JAK inhibitorsJAK/STATSTAT1 gain-of-functionSTAT3 gain-of-functionSTAT6 gain-of-functioninborn errors of immunity

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