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Updated: Sep 10, 2025

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

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Isolation, biosynthesis, and biological activity of pradimicins from actinomycetes

Yuhua Guo1, Fulai Yu1, Gang Li2

  • 1Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China; Key Laboratory of Biology and Cultivation of Herb Medicine (Haikou), Ministry of Agriculture and Rural Affairs, Haikou 571101, China; Key Laboratory of Tropical Crops Germplasm Resources Genetic Improvement and Innovation of Hainan Province, Haikou 571101, China; National Key Laboratory for Tropical Crop Breeding, Sanya 572024, China.

Bioorganic Chemistry
|August 22, 2025
PubMed

Keywords:
ActinomycetesBiological activityBiosynthesisNatural products isolationPradimicins

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