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Related Concept Videos

Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

164
Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
164

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Related Experiment Video

Updated: Sep 10, 2025

Author Spotlight: Assessment of Cardiac Output Calculation by Thermodilution in Pigs for Effective Perfusion Flow During EVLP
06:10

Author Spotlight: Assessment of Cardiac Output Calculation by Thermodilution in Pigs for Effective Perfusion Flow During EVLP

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Assessing Cardiac Flow Measurements Using a Noninvasive Photoplethysmography-Based Device Compared to Invasive

Dean Nachman1, Arik Eisenkraft2, Eldad Rahamim3

  • 1Heart Institute, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel; Institute for Research in Military Medicine, Faculty of Medicine, The Hebrew University of Jerusalem and the Israel Defense Force Medical Corps, Petah Tikva, Israel.

JACC. Advances
|August 22, 2025
PubMed
Summary

A new wearable photoplethysmography (PPG) device shows strong correlation with invasive methods for measuring cardiac output and systemic vascular resistance. This noninvasive monitor offers a promising alternative to traditional, riskier hemodynamic monitoring techniques.

Keywords:
Swan-Ganz cathetercardiac flow measurementscongestive heart failurenoninvasive monitoringphotoplethysmogramremote patient monitoring

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Area of Science:

  • Cardiovascular Physiology
  • Medical Device Technology
  • Biomedical Engineering

Background:

  • Invasive hemodynamic monitoring is the standard but carries significant risks.
  • Noninvasive methods are sought to improve patient safety and monitoring accessibility.

Purpose of the Study:

  • To compare a noninvasive wearable photoplethysmography (PPG)-based monitor against invasive pulmonary artery catheter measurements.
  • To evaluate the accuracy of PPG for cardiac output (CO) and systemic vascular resistance (SVR) monitoring.

Main Methods:

  • Heart failure patients undergoing right heart catheterization were enrolled.
  • PPG device readings were collected concurrently with invasive measurements (pulmonary artery catheter, indirect Fick, thermodilution).
  • Bland-Altman analysis and Pearson correlations assessed agreement and accuracy.

Main Results:

  • The PPG device demonstrated high correlation with invasive thermodilution for CO (Pearson r=0.959) and SVR (Pearson r=0.936).
  • Limits of agreement for CO were within ±30% compared to thermodilution (-19.1/14.5%).
  • Accurate correlations were observed across various patient BMIs and skin tones.

Conclusions:

  • The wearable PPG-based device shows excellent correlation with established invasive hemodynamic monitoring methods.
  • This noninvasive technology presents a viable and potentially safer alternative for hemodynamic assessment.