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Updated: Sep 10, 2025

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
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JTH in Clinic: Management of isolated distal deep vein thrombosis

Marc Righini1, Helia Robert-Ebadi1, Jean-Philippe Galanaud2

  • 1Division of Angiology and Hemostasis, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland.

Journal of Thrombosis and Haemostasis : JTH
|August 22, 2025
PubMed

Insights

Isolated distal deep vein thrombosis (DVT) management lacks clear guidelines. This paper offers a case-based approach to differentiate patients for ultrasound surveillance versus anticoagulant treatment, addressing a common clinical challenge.

Area of Science:

  • Vascular Medicine
  • Hematology
  • Diagnostic Imaging

Background:

  • Isolated distal deep vein thrombosis (DVT) constitutes up to 50% of lower limb DVTs identified via ultrasound.
  • Current management strategies for distal DVT are not well-established, leading to clinical practice variability.
  • Existing recommendations suggest ultrasound surveillance for select low-risk patients, but robust randomized data is limited.

Keywords:
anticoagulant therapycalf deep vein thrombosiscompression ultrasounddiagnosisdirect oral anticoagulantsdistal deep vein thrombosis

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