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Navigating complications of disease-modifying anti-rheumatic drugs at the 'front door'
1Rheumatology Research Group, Department of Inflammation and Ageing, School of Infection, Inflammation and Immunology, College of Medicine and Health, Queen Elizabeth Hospital, University of Birmingham, Mindelsohn Way, Birmingham, UK; Department of Rheumatology, University Hospitals Birmingham NHS Foundation Trust, Mindelsohn Way, Birmingham, UK.
Abstract:
Disease-modifying anti-rheumatic drugs (DMARDs) have revolutionised the treatment landscape in rheumatology, reducing both disease severity and the risk of systemic comorbidities. These immunomodulatory drugs have been repurposed for use in other chronic inflammatory diseases, conferring further advantages. However, DMARDs can be associated with adverse events that have implications for the management of common symptoms and conditions that present to medical services at the 'front door'.
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