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Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

26
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
26
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

25
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
25
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

27
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
27
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

17
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
17
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

204
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
204
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

238
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
238

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Updated: Sep 10, 2025

Isolation of Valvular Endothelial Cells
11:04

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Isolated Native Pulmonary Valve Endocarditis.

Aditya Mehta1, Sophie Miller2, Sonia Shah3

  • 1Department of Medicine, Harbor-UCLA Medical Center, Torrance, California, USA.

JACC. Case Reports
|August 22, 2025
PubMed
Summary
This summary is machine-generated.

Isolated native pulmonary valve endocarditis is rare, especially in cancer patients. Chest wall radiation can cause valvular degeneration, increasing endocarditis risk and potentially complicating diagnosis.

Keywords:
metastatic breast cancerpulmonary valve endocarditistransesophageal echocardiogramtransthoracic echocardiogramvalvular degeneration

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Oncology

Background:

  • Infective endocarditis (IE) typically affects the left heart valves.
  • Isolated native pulmonic valve endocarditis is an uncommon clinical presentation.

Observation:

  • A patient with stage IV breast cancer, previously treated with chest wall radiation and chemotherapy, presented with constitutional symptoms.
  • Echocardiography revealed isolated pulmonary valve endocarditis.

Findings:

  • Pulmonic valve endocarditis can be challenging to diagnose via echocardiography.
  • Valvular degeneration may initiate with radiation doses as low as 25 Gy.

Implications:

  • Chest wall radiation is an underrecognized risk factor for developing infective endocarditis.
  • Clinicians should maintain a high index of suspicion for pulmonic valve involvement in patients with relevant radiation history.