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Concurrent fibrillary glomerulopathy and amyloidosis: a diagnostic challenge

Tiffany N Caza1, Alejandro Best-Rocha1, Christopher P Larsen1

  • 1Arkana Laboratories, Little Rock, Arkansas, USA.

Kidney International
|August 22, 2025
PubMed
Abstract

No abstract available in PubMed .

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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
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