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Updated: Sep 10, 2025

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time
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Key determinants in implementation processes: a systematic review using the Consolidated Framework for Implementation

Marin Schmitt1, Maren Hawkins2, Paul Florsheim3

  • 1Zilber College of Public Health, University of Wisconsin-Milwaukee, 1240 N. 10th St., Milwaukee, WI, USA. marins@uwm.edu.

Implementation Science Communications
|August 22, 2025
PubMed
Summary

This review identified eight key determinants influencing health program implementation. Understanding these factors, such as leadership engagement and available resources, can improve implementation strategies and outcomes.

Keywords:
CFIRConsolidated Framework for Implementation ResearchDeterminantsImplementation scienceKey factorsSystematic review

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Area of Science:

  • Implementation Science
  • Health Services Research
  • Public Health

Background:

  • Contextual factors significantly impact health program implementation.
  • While many determinants are known, their relative influence requires further examination.
  • The Consolidated Framework for Implementation Research (CFIR) provides constructs for assessing implementation factors.

Purpose of the Study:

  • To systematically review studies that used the Damschroder & Lowery (2013) rating system.
  • To identify key determinants of implementation based on their impact.
  • To guide the development of effective health program implementation strategies.

Main Methods:

  • Forward citation searching of articles citing Damschroder & Lowery (2013) in PubMed, Web of Science, and Google Scholar.
  • Inclusion of articles examining the magnitude and valence of implementation factors.
  • Quality appraisal using the Mixed Methods Appraisal Tool (MMAT).

Main Results:

  • Forty-eight articles were included in the final review.
  • Eight key determinants were identified: Leadership Engagement, Formally Appointed Internal Implementation Leaders, Compatibility, Available Resources, External Change Agents, Champions, Relative Advantage, and Key Stakeholders.

Conclusions:

  • Identifying key determinants can enhance the systematic approach to implementation.
  • This knowledge aids researchers and practitioners in facilitating successful implementation efforts.
  • Quantifying determinant impact, despite nuance loss, offers practical guidance for improving implementation outcomes.