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Related Experiment Videos

Percutaneous coagulum nephrolithotripsy: a new approach.

R Hasun, P C Ryan, A B West

    British Journal of Urology
    |December 1, 1985
    PubMed
    Summary

    A new gelatine (Lithogel) prevents kidney stone fragments from scattering during percutaneous nephrolithotripsy. This innovative approach reduces post-operative pain and further stone formation by containing fragments within the gel.

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    Area of Science:

    • Urology
    • Nephrology
    • Biomaterials

    Background:

    • Intrarenal stone fragment scatter during percutaneous nephrolithotripsy (PCNL) can lead to complications.
    • These complications include increased post-operative pain and secondary stone formation.
    • Percutaneous introduction of coagulums to prevent scatter has faced challenges.

    Purpose of the Study:

    • To describe a novel gelatine-based agent, Lithogel, for preventing intrarenal stone fragment scatter during PCNL.
    • To evaluate the safety and efficacy of Lithogel in managing stone fragments within the renal collecting system.

    Main Methods:

    • An experimental study was conducted using Lithogel, a new gelatine formulation.
    • Lithogel was introduced percutaneously through a nephroscope to coat renal calculi.

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  • The study assessed the agent's ability to facilitate calculus disintegration and prevent fragment migration.

    • Main Results:

    • Lithogel effectively coats renal calculi, facilitating their disintegration within the gel matrix.
    • The agent demonstrated safety during experimental use.
    • Lithogel successfully prevented the scatter of stone fragments into inaccessible calices.

    Conclusions:

    • Lithogel presents a safe and effective method for preventing intrarenal stone fragment scatter during PCNL.
    • This novel approach may help mitigate post-operative pain and reduce the risk of further stone formation.
    • The per-nephroscope delivery system simplifies the application of Lithogel.