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Levofloxacin in Bone and Joint Infections: Development of an Application for Model-Informed Precision Dosing

Léo Mimram1, Sophie Magreault1,2, Florian Lemaitre3

  • 1Université Paris Cité and Université Sorbonne Paris Nord, Inserm, IAME, Paris, France.

Clinical Pharmacology and Therapeutics
|August 23, 2025
PubMed
Summary

Bayesian estimation accurately predicts levofloxacin exposure (AUC0-24) for bone infections using limited sampling. A free web app aids precision dosing, though Cmax estimation remains challenging.

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