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Insulin resistance mediates the association between sedentary behavior and depression: Evidence from a large-scale

Xun Huang1, Xiaoyang Yao2, Min Fang2

  • 1Department of Cardiovascular Medicine, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No. 1, Minde Road, Donghu District, Nanchang 330006, Jiangxi Province, China; Department of Cardiovascular Medicine, Jiangxi Province Hospital of Integrated Chinese and Western Medicine, No. 90, Bayi Avenue, Xihu District, Nanchang 330003, Jiangxi Province, China.

Journal of Affective Disorders
|August 23, 2025
PubMed
Abstract

Keywords:
DepressionInsulin resistanceMETS-IRMediation analysisNHANESSedentary behaviorSex differences

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