Related Experiment Video

Updated: Sep 10, 2025

Label-Free Imaging of Lipid Storage Dynamics in Caenorhabditis elegans using Stimulated Raman Scattering Microscopy
10:59

Label-Free Imaging of Lipid Storage Dynamics in Caenorhabditis elegans using Stimulated Raman Scattering Microscopy

Published on: May 28, 2021

4.3K

Sterol analysis of MARCHF6-deficient cells reveals a new pinch point in the cholesterol biosynthesis pathway

Nicole M Fenton1, Laura J Sharpe1, Andrew M Jenner2

  • 1School of Biotechnology and Biomolecular Sciences, UNSW, Sydney, NSW 2052, Australia.

Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids
|August 23, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
CholesterolE3 ubiquitin ligaseMARCHF6Post-translational regulation

More Related Videos

Cholesterol Efflux Assay
07:54

Cholesterol Efflux Assay

Published on: March 6, 2012

30.0K
Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol
10:12

Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol

Published on: March 25, 2020

6.2K

Related Experiment Videos

Last Updated: Sep 10, 2025

Label-Free Imaging of Lipid Storage Dynamics in Caenorhabditis elegans using Stimulated Raman Scattering Microscopy
10:59

Label-Free Imaging of Lipid Storage Dynamics in Caenorhabditis elegans using Stimulated Raman Scattering Microscopy

Published on: May 28, 2021

4.3K
Cholesterol Efflux Assay
07:54

Cholesterol Efflux Assay

Published on: March 6, 2012

30.0K
Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol
10:12

Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol

Published on: March 25, 2020

6.2K

Related Concept Videos

Cholesterol: Significance and Regulation01:29

Cholesterol: Significance and Regulation

678
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
678

Articles linked to this work by shared authors, journal, and citation graph.

International Union of Basic and Clinical Pharmacology. CXXII. Applying an objective evaluation to the status of class A orphan G protein-coupled receptors.

Pharmacological reviews·2026

Phosphatidylserine transporters ORP5 and ORP8 control cholesterol trafficking from the plasma membrane to the endoplasmic reticulum.

Journal of lipid research·2026

Balancing cholesterol metabolism in the liver and gut: perspectives in health and disease.

Nature reviews. Gastroenterology & hepatology·2026

The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors.

British journal of pharmacology·2025

CHP1 promotes lipid droplet growth and regulates the localization of key enzymes for triacylglycerol synthesis.

Proceedings of the National Academy of Sciences of the United States of America·2025

Comprehensive survey of disease-causing missense mutations of the cholesterol synthesis enzyme NSDHL: Low temperature and a chemical chaperone rescue low protein expression of select mutants.

The Journal of steroid biochemistry and molecular biology·2025

Neuronal fatty acid bioenergetics: An emerging pathway and potential point in convergence in hereditary spastic paraplegias.

Biochimica et biophysica acta. Molecular and cell biology of lipids·2026

DHA increases Angptl4 gene expression and reduces LPL activity in a PPARγ-dependent manner in adipocytes.

Biochimica et biophysica acta. Molecular and cell biology of lipids·2026

HCV clearance by direct-acting antivirals reduces serum phosphatidylethanolamine and improves phospholipid balance.

Biochimica et biophysica acta. Molecular and cell biology of lipids·2026

ApoE deficiency in mice exacerbates antigen-induced arthritis, alters HDL anti-oxidant capacity and promotes macrophage activation which are reversed by simvastatin treatment.

Biochimica et biophysica acta. Molecular and cell biology of lipids·2026

Retinoic acid-inducible prostaglandin I2 receptor is required for the development of proximal tubules in zebrafish.

Biochimica et biophysica acta. Molecular and cell biology of lipids·2026

A sweet potato vine-derived peptide ST2b alleviates type 2 diabetes via stabilizing INSIG-1 to inhibit SREBP-2-driven lipotoxicity.

Biochimica et biophysica acta. Molecular and cell biology of lipids·2026

Intra-Pancreatic Fat Deposition Versus Hepatic Fat in Relation to Incident Heart Failure: A Prospective Cohort Analysis.

Reviews in cardiovascular medicine·2026

Early postoperative body-composition trajectories and exploratory ratio-defined phenotypes after laryngectomy for laryngeal cancer: a prospective cohort study.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2026

Uric acid-associated psychopathology in first-episode drug-naïve schizophrenia stratified by depressive symptoms.

Journal of neural transmission (Vienna, Austria : 1996)·2026

Physiological vs risk-relevant lipid remodeling across the menopausal transition: FMP-anchored trajectories, male benchmarking, LDLR genetics, risk calibration, and incident MACE in 273,036 UK Biobank women.

Journal of clinical lipidology·2026

Lacticaseibacillus paracasei CM6 postbiotics alleviate SO/SP-induced hepatic lipotoxicity in HepG2 cells: Insights into lipid-redox homeostasis, glutamate metabolism and PLA2G4A-dependent lysophospholipid remodeling.

Food research international (Ottawa, Ont.)·2026

Supramolecular engineering of a ferulic acid-puerarin co-amorphous system via intermolecular hydrogen bonding: Mechanism, enhanced bioavailability, and synergistic lipid-lowering efficacy.

Food research international (Ottawa, Ont.)·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us