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Transport-Related Risk Factors for Intraventricular Hemorrhage in Preterm Neonates: An Exploratory Analysis

Colleen Butler1, Julianne Olshannikov1, Jennifer Watts1

  • 1Advocate Children's Hospital Neonatal Pediatric Transport Program, Elmhurst, IL.

Air Medical Journal
|August 23, 2025
PubMed

Insights

Intraventricular hemorrhage (IVH) in preterm infants is linked to maternal infections and infant positioning during transport. Male neonates and midline positioning were associated with IVH, emphasizing modifiable factors for prevention.

Area of Science:

  • Neonatal care
  • Transport medicine
  • Neuroprotection

Background:

  • Preterm neonates are at high risk during ground transport.
  • Neuroprotection is crucial to prevent intraventricular hemorrhage (IVH).
  • Transport-related factors contributing to IVH are not well understood.

Purpose of the Study:

  • Identify transport-related factors associated with IVH in preterm neonates.
  • Examine the link between critical ground transport parameters and clinical IVH factors.
  • Assess the impact of maternal and fetal factors on IVH development.

Main Methods:

  • Retrospective study using electronic health records from two Midwest transport teams.
  • Logistic regression models were employed to analyze transport and maternal variables.
  • Data from 79 preterm neonates were analyzed.

Main Results:

  • 25 (31.6%) neonates developed IVH.
  • Higher IVH incidence observed in male neonates (P = .02).
  • Midline positioning was associated with IVH status (P = .03).
  • Maternal infection significantly correlated with IVH (OR = 6.17, P = .0288).
  • No association found between critical ground transport factors and IVH rates.

Conclusions:

  • Maternal infections and infant positioning are modifiable factors for IVH prevention.
  • Optimizing ground transport practices is essential, especially for male neonates.
  • Further research into transport-related IVH factors is warranted.

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