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Updated: Sep 10, 2025

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Advancing Global Cancer Symptom Science: Insights and Strategies From the Inaugural Cancer Symptom Science Expert
Sara Colomer-Lahiguera1, Rachel A Pozzar2, Carolyn S Harris3
1Sara Colomer-Lahiguera.
Oncology Nursing Forum
|August 24, 2025
Summary
Nurse scientists established the Global Research Alliance in Symptom Science (GRASS) to advance cancer symptom research. This alliance aims to improve data collection, develop common data models, and enhance clinical implementation strategies globally.
Area of Science:
- Symptom science research
- Oncology
- Chronic disease management
Background:
- The inaugural Cancer Symptom Science Expert Meeting convened 40 nurse scientists from seven countries in Lausanne, Switzerland.
- The meeting focused on enhancing global collaboration, identifying research gaps, and strategizing to accelerate international symptom science.
- Discussions included the co-occurrence of cancer with other chronic conditions and shared underlying mechanisms.
Purpose of the Study:
- To summarize discussions and recommendations from the Cancer Symptom Science Expert Meeting.
- To introduce the Global Research Alliance in Symptom Science (GRASS).
Main Methods:
- Presentations highlighted critical issues and unanswered questions in cancer symptom science and chronic conditions.
- Four core topic areas were identified based on knowledge gaps.
- Four working groups (WGs) were formed to identify gaps, opportunities, and strategic actions.
Main Results:
- WG1: Recommendations on optimal collection, analysis, and use of symptom data.
- WG2: Development of a minimum dataset or common data model for symptom science.
- WG3: Enhancement of implementation science strategies for clinical practice.
- WG4: Capacity building and infrastructure for the Global Research Alliance in Symptom Science (GRASS).
Conclusions:
- WG recommendations demonstrate international commitment to advancing symptom science.
- The meeting laid the groundwork for establishing GRASS, a global research alliance.
- Future directions include regular meetings, interprofessional collaboration, and engagement with symptom scientists.
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