Exploring antimicrobial soda-lime glasses as glaze alternatives for 4Y-PSZ
- 1Department of Dental Materials and Prosthodontics, Institute of Science and Technology, São Paulo State University (UNESP), São José dos Campos, SP, Brazil.
- 2Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (UNESP), São José dos Campos, SP, Brazil.
- 3Department of Physics, Aeronautics Technological Institute (ITA), São José dos Campos, SP, Brazil; Graduate Program in Dentistry, Federal University of Pelotas (UFPel), Pelotas, RS, Brazil.
- 0Department of Dental Materials and Prosthodontics, Institute of Science and Technology, São Paulo State University (UNESP), São José dos Campos, SP, Brazil.
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August 24, 2025
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View abstract on PubMed
Summary
This summary is machine-generated.Two experimental glass coatings on 4Y-PSZ ceramics offer antimicrobial benefits without compromising mechanical or optical properties. The soda-lime (SL) coating demonstrated both immediate and lasting antimicrobial effects, inhibiting Candida albicans hyphae formation.
Area Of Science
- Biomaterials Science
- Dental Ceramics
- Antimicrobial Materials
Background
- 4Y-PSZ (tetragonal zirconia polycrystal) ceramics are widely used in dental restorations.
- Developing functional coatings for dental ceramics is crucial for enhancing their clinical performance.
- Investigating novel glass coatings for improved antimicrobial properties without compromising existing material characteristics is essential.
Purpose Of The Study
- To evaluate the mechanical, optical, and antimicrobial effects of experimental soda-lime (SL) and silver-containing soda-lime (Ag) glass coatings on 4Y-PSZ.
- To compare these experimental coatings with a commercial glaze (G).
Main Methods
- Experimental SL and Ag glass powders were applied and fused onto 4Y-PSZ disc specimens.
- Coated specimens were analyzed for roughness, translucency, and biaxial flexural strength.
- Microstructural analysis using scanning electron microscopy was performed.
- Antimicrobial efficacy against Candida albicans, Streptococcus sanguinis, and Streptococcus mutans was assessed using colony-forming unit (CFU) assays on initial and aged specimens.
Main Results
- Mechanical (flexural strength) and optical (translucency) properties, as well as roughness, were comparable across all groups (SL, Ag, G).
- Both SL and Ag coatings exhibited antimicrobial activity against S. sanguinis and S. mutans.
- The SL coating showed a notable reduction in C. albicans hyphal formation and maintained antimicrobial effects over time, unlike the Ag coating which required aging.
Conclusions
- Experimental SL and Ag glass coatings can be applied to 4Y-PSZ without negatively impacting key mechanical and optical properties.
- The SL coating provides significant, sustained antimicrobial benefits, including inhibition of C. albicans hyphae, making it a promising candidate for dental applications.
- These findings suggest potential for enhanced functional dental restorations using novel glass coatings.
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