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Mapping Nutrition and Tuberculosis Research: Insights From Bibliometric Perspective
Chenqi Li1,2, Biao Gao3, Hongmei Xiao4
1Department of Naval Nutrition and Food Hygiene, Naval Medical University, Shanghai, China.
This study maps the research landscape of nutrition and tuberculosis (TB). Findings show a shift towards integrated networks, with Vitamin D central, and highlight gut microbiota and fatty acids as emerging research frontiers for TB management.
Area of Science:
- Nutritional Immunology
- Infectious Disease Research
- Bibliometrics
Background:
- Malnutrition and tuberculosis (TB) present a detrimental cycle impacting patient outcomes.
- Existing research on nutritional interventions for TB lacks a clear structural and frontier characterization.
Purpose of the Study:
- To systematically analyze the research structure, evolution, and frontiers in the nutrition-TB field.
- To utilize bibliometric methods for a comprehensive knowledge mapping of this research area.
Main Methods:
- Bibliometric analysis of 4502 records from the Web of Science Core Collection (2007-present).
- CiteSpace software used for co-occurrence, timeline visualization, and burst detection of keywords, citations, and authors.
- Network centrality metrics applied to identify key research nodes.
Main Results:
- Vitamin D is a central research node, linking basic science to clinical TB applications.
- Research evolved from molecular mechanisms to clinical validation and systems biology integration.
- Emerging frontiers include gut microbiota and fatty acids; diabetes-TB comorbidity highlights metabolic-immune interactions.
Conclusions:
- Nutrition-TB research is moving towards integrated 'nutrition-microbiome-metabolism-immunity' networks.
- Future research should prioritize precision nutrition, multi-omics, and clinical translation, especially for high-risk populations.
- High citation of WHO reports underscores the need for policy translation.
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