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Related Experiment Video

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Gyroscopic Stereotactic Radiosurgery: A Retrospective Analysis.

Dylan R Conroy1, Susan M Woody1, Ying E Niu1

  • 1Radiation Oncology, MedStar Georgetown University Hospital, Washington, DC, USA.

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|August 25, 2025
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Summary

This study evaluates a new gyroscopic radiosurgery system for brain tumors, showing 95% local control with minimal toxicity. The novel platform offers efficient and effective treatment comparable to existing stereotactic radiosurgery methods.

Keywords:
brain stereotactic radiosurgeryradio-neurosurgerystereotactic srszapzap-x radiosurgical system

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Area of Science:

  • Neurosurgery
  • Radiation Oncology
  • Medical Physics

Background:

  • Stereotactic radiosurgery (SRS) is a standard treatment for brain tumors.
  • A novel gyroscopic, frameless, self-contained, and self-shielded radiosurgery system has been developed.
  • This system features a 2.7-MV linear accelerator with onboard image guidance.

Purpose of the Study:

  • To present the initial clinical experience with this new gyroscopic radiosurgery system.
  • To evaluate the safety, efficacy, and dosimetric performance of the novel platform.
  • To assess treatment outcomes including local control and toxicity.

Main Methods:

  • Retrospective analysis of 30 patients treated between September 2020 and July 2023.
  • Treatment of 107 lesions including brain metastases, skull base tumors, and arteriovenous malformations.
  • Data collection on delivered doses, treatment times, dosimetric parameters, and toxicity.

Main Results:

  • 95% local control was achieved at a median follow-up of 14.7 months.
  • Median treatment time was 24 minutes per lesion with a median of 74 beams.
  • Acute toxicity was observed in 16.2% of patients; late toxicity included radiation necrosis and Bell's palsy, with no grade 4+ events.

Conclusions:

  • The gyroscopic radiosurgery system demonstrates functionality, performance efficiency, and dosimetric benefits.
  • Treatment outcomes align with historical data from other SRS modalities.
  • This represents one of the largest published clinical experiences with gyroscopic radiosurgery to date.