Related Experiment Video
Updated: Sep 10, 2025

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
Resistant hypertension treated with laparoscopic-assisted renal denervation in a patient with end-stage renal
Jiapeng Chu1, Xiaolong Liu2, Chunlai Shao1
1Department of Cardiology, The Second Affiliated Hospital of Soochow University, 1055 Sanxiang Rd., Gusu District, Suzhou, Jiangsu 215004, China.
Background:
In patients with end-stage renal disease (ESRD) on dialysis, hypertension is commonly detected and inadequately controlled despite the use of multiple anti-hypertensive medications. Sympathetic hyperactivation is a key feature in chronic kidney disease and can be targeted by renal denervation (RDN).
Case Summary:
A 47-year-old male patient with pharmacologically resistant hypertension and ESRD on peritoneal dialysis underwent radiofrequency renal nerve ablation using a laparoscopic-assisted system. During the 6-month follow-up after the operation, we observed a remarkable and sustained reduction in blood pressure, with a significant decrease in oral anti-hypertensive medications.
Discussion:
This case demonstrates the safety and effectiveness of laparoscopic-assisted RDN for lowering blood pressure. This technology, as an alternative to catheter-based RDN, bears the potential for wider application in high-risk patients with severe renal failure.
More Related Videos
04:37Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
08:505/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
Related Concept Videos
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme...
Antihypertensive Drugs: Direct Renin Inhibitors
Kidney Transplant II: Surgical Procedure
Heart Failure V: Medical Management
Dialysis
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...