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Author Spotlight: Assessing the Potential of Circulating Tumor Cells in Leptomeningeal Disease Research
Published on: March 29, 2024
A Comprehensive Case Report of Metastatic Intracranial Melanoma with Brief Review of Literature
Prachi Prachi1, Hema Malini Aiyer1, Gaurav Sharma1
1Department of Anatomic Pathology, Dharamshila Narayana Superspeciality Hospital and Research Centre, Vasundhara Enclave, New Delhi, India.
Abstract:
Primary intracranial melanomas are an extremely rare entity and are a diagnosis of exclusion. Malignant melanoma represents the third most common site for cerebral metastasis. We hereby narrate a comprehensive and detailed case of metastatic intracranial melanomas with BRAF mutation, which later on had an extensive systemic spread. The imaging differentials include metastasis, intracranial hemorrhage, or granuloma. The final and definitive diagnosis was attained by detailed clinical, histological, and immunohistochemical evaluation as metastatic malignant pigmented tumor consistent with intracranial melanoma.

