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Detection and Predictors of Arrhythmia in Patients with Chronic Noncardioembolic Ischemic Stroke on Wearable
Yu Akimoto1, Yoshiro Ito1, Hideo Tsurushima1,2
1Department of Neurosurgery, Institute of Medicine, University of Tsukuba, Ibaraki, Japan.
Insights
Frequent premature ventricular contractions (PVCs) are more common in patients with chronic noncardioembolic ischemic stroke. A wearable device effectively screens for arrhythmias in this population.
Area of Science:
- Cardiology
- Neurology
- Medical Devices
Background:
- Screening for arrhythmias in patients with chronic noncardioembolic ischemic stroke is currently limited.
- Arrhythmias can increase the risk of recurrent stroke.
Purpose of the Study:
- To investigate the prevalence of arrhythmia in patients with chronic noncardioembolic ischemic stroke.
- To evaluate the utility of a stick-on wearable device for arrhythmia detection in this patient group.
Main Methods:
- A prospective observational study was conducted with 176 patients with a history of noncardioembolic ischemic stroke.
- Patients wore a stick-on wearable device for approximately 7 days to monitor for arrhythmias.
- Patients on anticoagulant therapy were excluded from the study.
Main Results:
- The study found a high prevalence of frequent premature atrial contractions (PACs) at 39.2% and frequent premature ventricular contractions (PVCs) at 20.5%.
- Age and cilostazol use were identified as independent risk factors for frequent PACs.
- Age, male sex, and cilostazol use were independently associated with frequent PVCs.
Conclusions:
- The prevalence of frequent PVCs in patients with chronic noncardioembolic ischemic stroke is higher than in the general population.
- A stick-on wearable device is a valuable tool for screening arrhythmias in patients with chronic noncardioembolic ischemic stroke.
Objectives:
The screening examination for arrhythmias in patients with chronic noncardioembolic ischemic stroke is limited. This study aimed to investigate the prevalence of arrhythmia in patients with chronic noncardioembolic ischemic stroke using a stick-on wearable device.
Materials And Methods:
This was a prospective observational study conducted between July 2020 and February 2022 involving 176 patients with a history of noncardioembolic ischemic stroke. Patients receiving anticoagulant therapy were excluded. For the evaluation of arrhythmias, the patients wore a stick-on wearable device for a maximum of approximately 7 days. We investigated the prevalence of arrhythmia and its associated factors.
Results:
The mean measurement time was 121.3 ± 45.3 hours. Atrial fibrillation was present in 2 (1.1%) patients, frequent premature atrial contractions (PACs) in 69 (39.2%), and frequent premature ventricular contractions (PVCs) in 36 (20.5%). Regression analysis showed that the risk factors independently associated with frequent PACs were age (odds ratio [OR] 1.103, 95% confidence interval [CI] 1.055-1.153; p < 0.001) and cilostazol use (OR 2.681, 95% CI 1.338-5.371; p = 0.005). Regression analysis showed that the risk factors independently associated with frequent PVCs were age (OR 1.047, 95% CI 1.002-1.095; p = 0.043), male sex (OR 3.834, 95% CI 1.441-11.045; p = 0.013), and cilostazol use (OR 2.968, 95% CI 1.363-6.463; p = 0.006).
Conclusion:
The prevalence of frequent PVCs is higher in patients with chronic noncardioembolic ischemic stroke than in the general population. The stick-on wearable device is a useful screening tool for arrhythmia in patients with chronic noncardioembolic ischemic stroke.
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