Fetoscopic Reduction and Closure for Complex Gastroschisis: A Novel Minimally Invasive Prenatal Approach
Gustavo Yano Callado1, Edward Araujo Júnior1,2,3, Adriane Sakae Tsujita4
1Albert Einstein Israelite College of Health Sciences, Albert Einstein Israelite Hospital, São Paulo, SP Brazil.
Journal of Obstetrics and Gynaecology of India
|August 25, 2025
Summary
Fetoscopic fetal surgery successfully corrected gastroschisis (a congenital abdominal wall defect) in utero. This minimally invasive technique shows promise for favorable neonatal outcomes and early discharge without further surgery.
Area of Science:
- Fetal Medicine
- Minimally Invasive Surgery
- Neonatal Surgery
Background:
- Gastroschisis is a congenital defect involving fetal intestinal herniation through an abdominal wall opening.
- Current standard treatment involves postnatal surgical repair.
- Fetoscopic fetal surgery is an emerging intervention for complex cases.
Purpose of the Study:
- To document a fetoscopic technique for in utero gastroschisis correction.
- To evaluate the feasibility and safety of this minimally invasive approach.
- To report neonatal outcomes following in utero repair.
Main Methods:
- A case report detailing a fetoscopic gastroschisis repair at 29 weeks gestation.
- Ultrasound guidance was used to introduce a fetoscope and trocars into the amniotic cavity.
- Herniated intestines were repositioned, and the abdominal wall defect was closed using continuous suture.
Main Results:
- The procedure was completed in 80 minutes with continuous fetal vitality monitoring.
- A healthy female infant was delivered at 32 weeks gestation.
- The newborn exhibited normal gastrointestinal function and was discharged at 14 days without requiring additional surgery.
Conclusions:
- Fetoscopic repair of gastroschisis is feasible and safe, leading to favorable neonatal outcomes.
- This technique resulted in early discharge and avoidance of further surgical interventions.
- Further investigation via randomized clinical trials is warranted to compare this approach with standard postnatal treatment.


