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Retrograde intussusception in pregnancy following Roux-en-Y gastric bypass: a case report
Mahmoud K Abd-El-Hafez1, Todd D Beyer2, Megan K Applewhite2
1Albany Medical College, School of Allopathic Medicine, 43 New Scotland Ave, Albany, NY 12208, United States.
Journal of Surgical Case Reports
|August 25, 2025
Summary
Retrograde intussusception, a rare condition, occurred in a pregnant woman after gastric bypass surgery. This case highlights the importance of considering rare complications in high-risk pregnancies.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Obstetrics
Background:
- Retrograde intussusception is a rare form of bowel invagination, typically occurring anterograde due to peristalsis.
- Roux-en-Y gastric bypass procedures can predispose patients to rare gastrointestinal complications.
- Pregnancy presents unique physiological challenges that can alter the presentation and management of surgical conditions.
Observation:
- A 23-year-old pregnant female (36 weeks gestation) presented with acute abdominal pain, nausea, and hematemesis.
- Symptoms were attributed to retrograde intussusception at the jejunojejunostomy anastomosis, occurring 3 years post-Roux-en-Y gastric bypass.
- Diagnosis was confirmed via CT scan and exploratory laparotomy.
Findings:
- Surgical resection of the affected jejunojejunostomy and proximal jejunal common channel was performed.
- A new jejunojejunostomy anastomosis was successfully reconstructed.
- The patient was discharged on postoperative day 9 with anticoagulation for superior mesenteric vein thrombosis.
Implications:
- This case underscores the rarity of retrograde intussusception in pregnant patients post-gastric bypass.
- Early diagnosis and surgical intervention are crucial for favorable outcomes in such complex cases.
- Further research is warranted to understand the specific risk factors and optimal management strategies.

