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Updated: Sep 10, 2025

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Upper endoscopy in Solomon Islands: A four-year retrospective study.

Dylan M Bush1, Stallone Kohia2,3, Adrian Garcia Hernandez4

  • 1Division of Biology and Medicine, The Warren Alpert Medical School of Brown University, Providence, RI, USA.

Science Progress
|August 25, 2025
PubMed
Summary

Gastrointestinal disease is a concern in the Solomon Islands, with common findings of erosions and ulcers despite low rapid urease test (RUT) positivity. Further research into non-invasive H. pylori testing is recommended.

Keywords:
EndoscopySolomon Islandsgastric cancergastroscopypeptic ulcer disease

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Area of Science:

  • Gastroenterology
  • Epidemiology
  • Public Health

Background:

  • Gastrointestinal diseases are prevalent globally, but data from the Solomon Islands is limited.
  • Flexible endoscopy was introduced to the Solomon Islands National Referral Hospital (NRH) in 2012, yet understanding of local gastrointestinal pathology remains scarce.

Purpose of the Study:

  • To describe trends in upper gastrointestinal diseases in the Solomon Islands.
  • To inform local research and health programming by analyzing endoscopic and H. pylori data.

Main Methods:

  • A retrospective cohort study analyzing demographic, clinical, and endoscopic data from NRH patient records (2019-2022).
  • Included rapid urease test (RUT) results for H. pylori detection.
  • Data abstracted from consecutively entered patient medical records.

Main Results:

  • 761 patients underwent upper endoscopy and RUT. RUT was positive in 25.8% (196/761).
  • Common findings included erosions (11.8%) and ulcers (11.7%), with 22.1% presenting with upper gastrointestinal bleeding.
  • H. pylori treatment failure was observed in 28.8% of patients with follow-up data. Age was associated with ulcers; gastric erythema/erosions with duodenitis; melena/hematemesis with ulcers.

Conclusions:

  • Significant gastrointestinal symptomology and pathology were observed in the Solomon Islands cohort.
  • Endoscopy and RUT access are limited to one unit in the Solomon Islands.
  • Future efforts should focus on non-invasive H. pylori testing and ulcer disease management strategies.