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Updated: Sep 10, 2025

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins
09:07

Electroconvulsive Seizures in Rats and Fractionation of Their Hippocampi to Examine Seizure-induced Changes in Postsynaptic Density Proteins

Published on: August 15, 2017

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Electroconvulsive therapy and the WHO: patients and professionals deserve expertise and facts, not ideology

David Zilles-Wegner1, Alexander Sartorius2

  • 1Klinik für Psychiatrie und Psychotherapie, Universitätsmedizin Göttingen, Georg-August-Universität, Von-Siebold-Str. 5, 37075, Göttingen, Germany. david.zilles@med.uni-goettingen.de.

Der Nervenarzt
|August 25, 2025
PubMed
Abstract

No abstract available in PubMed .

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Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
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