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Technique and outcomes of robotic median arcuate ligament release in 52 patients: a multidisciplinary experience
Andrea Simioni1, Gloria Jung2, Cameron Villarreal1
1Division of Gastrointestinal Surgery, Department of Surgery, University of Colorado, 12631 E. 17th Avenue, Room 6001, Mail Stop C313, Aurora, CO, 80045, USA.
Abstract:
Despite previous reports of robotic-assisted release for median arcuate ligament syndrome (MALS), the safety and efficacy of this approach have been difficult to establish due to the rarity of the disease. We aimed to present our experience at a tertiary surgery referral center. We performed a retrospective analysis of all robotic-assisted median arcuate ligament release (rMALR) performed at our institution from 7/2019 to 5/2025. The diagnosis was based on symptoms at presentation, celiac artery duplex ultrasound, and findings on computed tomographic angiography. The primary outcomes include resolution of symptoms at 6 weeks, 1 year, and 2 years follow-up. Secondary outcomes include resolution of narcotic use, operative time, 30-day mortality, length of stay, and postoperative complications. 52 patients underwent robotic MALR; 94% were females, with a mean age of 39 (18.2-52) years and a mean BMI of 21.2 kg/m2. The most common presenting symptoms were postprandial pain (98%) and weight loss (81%). Celiac stenosis greater than 70% was observed in all cases. Fifty-one (98%) cases were completed robotically; one case required conversion to laparotomy. The mean operative time was 224 (95-310) minutes, and the mean blood loss was 463 (25-850) ml. Follow-up duration was 38 (9-77) months. Resolution of symptoms was 96%, 92%, and 88% at 6 weeks, 1 year, and 2 years follow-up, respectively. Our experience demonstrates that robotic MALR is safe and effective in selected patients. A multidisciplinary approach and thorough preoperative workup are key to the successful treatment of MALS.
Insights
Robotic-assisted release for median arcuate ligament syndrome (MALS) is safe and effective. This study shows high symptom resolution rates and minimal complications in selected patients, highlighting the importance of a multidisciplinary approach.
Area of Science:
- Minimally Invasive Surgery
- Gastrointestinal Surgery
- Vascular Surgery
Background:
- Median arcuate ligament syndrome (MALS) is a rare condition causing abdominal pain.
- Previous reports on robotic-assisted release for MALS lack extensive data.
- Establishing the safety and efficacy of robotic approaches is crucial.
Purpose of the Study:
- To evaluate the safety and efficacy of robotic-assisted median arcuate ligament release (rMALR).
- To present institutional experience from a tertiary surgery referral center.
- To assess long-term outcomes of rMALR for MALS.
Main Methods:
- Retrospective analysis of 52 patients undergoing rMALR from 7/2019 to 5/2025.
- Diagnosis confirmed by symptoms, celiac artery duplex ultrasound, and CT angiography.
- Primary outcomes: symptom resolution at 6 weeks, 1 year, and 2 years.
Main Results:
- 98% of patients were female, mean age 39 years, mean BMI 21.2 kg/m².
- 96%, 92%, and 88% symptom resolution at 6 weeks, 1 year, and 2 years, respectively.
- Mean operative time 224 minutes; 98% cases completed robotically.
Conclusions:
- Robotic MALR is a safe and effective treatment for selected MALS patients.
- High rates of symptom resolution and minimal complications observed.
- Multidisciplinary approach and thorough preoperative workup are essential for successful MALS treatment.

