Related Experiment Video
Updated: Sep 10, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Testing Bidirectional Associations Between Maternal and Child Depression During Emerging Adolescence.
Jackson M A Hewitt1,2,3, Brae Anne McArthur1,2, Ross D Neville4
1Department of Psychology, University of Calgary, Calgary, Alberta, Canada.
Child depression may worsen maternal depression, challenging prior assumptions. This bidirectional link, particularly in higher-income families, underscores the need for family-centered mental health care.
Area of Science:
- Child and Adolescent Psychiatry
- Developmental Psychology
- Mental Health Research
Background:
- Parental depression is often assumed to precede and influence child depression.
- The reverse directionality, where child depression impacts parental mental health, is less understood.
- Clarifying these associations is crucial for effective family-centered pediatric care.
Purpose of the Study:
- To examine the longitudinal, bidirectional relationship between maternal and child depression.
- To investigate these associations from middle childhood through emerging adolescence.
- To assess the moderating role of sociodemographic factors, including income, during the COVID-19 pandemic.
Main Methods:
- Longitudinal cohort study (All Our Families) in Calgary, Alberta, Canada.
- Data collected across multiple waves from children aged 10.3 to 12.8 years.
- Random-intercept cross-lagged panel models analyzed maternal and child depressive symptoms.
Main Results:
- Cross-sectional correlations showed stable associations between maternal and child depression.
- Increases in child depression predicted subsequent increases in maternal depression.
- This child-to-parent effect was more pronounced in higher-income households and moderated by income.
Conclusions:
- Findings challenge the traditional view, suggesting child depression can contribute to maternal depression.
- The bidirectional link highlights the interconnectedness of parental and child mental health.
- Emphasizes the importance of family-centered interventions in pediatric mental health care.
Related Concept Videos
Socioemotional Development during Infancy
Primary Temperament Types
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Cognitive Development During Adolescence
Depression: Overview
Psychological and Sociocultural Causes of Schizophrenia
Depressive Disorders: MDD and Dysthymia

