Visualizing and analyzing global knowledge maps and emerging research trends in tumor-derived exosomes using...

Area of Science:

• Biomedical research
• Cancer diagnostics and therapeutics
• Exosome biology

Background:

• Tumor-derived exosomes show promise for disease diagnosis and treatment.
• Understanding research trends is crucial for advancing the field.

Purpose of the Study:

• To conduct a bibliometric analysis of tumor-derived exosome research.
• To identify current research hotspots and predict future trends.
• To provide insights for future research directions.

Main Methods:

• Bibliometric analysis of 2523 English-language articles from 2015-2024.
• Utilized CiteSpace software for visualization and analysis.
• Conducted co-occurrence, clustering, and emergence analyses of references.

Main Results:

• A consistent increase in publications over the last decade.
• China and the United States lead in productivity and influence, respectively.
• Prominent research focuses include exosomal PD-L1 mechanisms and engineered exosomes.

Conclusions:

• Current research concentrates on exosome PD-L1 mechanisms and engineered exosomes.
• Future research is expected to explore engineered exosomes for tumor cell targeting.
• Engineered exosomes show potential as drug delivery platforms for precise therapeutics.