Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

MicroRNAs01:22

MicroRNAs

21.1K
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After...
21.1K
MicroRNAs01:22

MicroRNAs

3.0K
MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
3.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effectiveness of game-based learning in mental health nursing education on self-directed learning and academic self-efficacy among nursing students.

BMC medical education·2026
Same author

Evaluating the effectiveness of substance use disorder treatment centers: a systematic review of international standards and outcomes.

Substance abuse treatment, prevention, and policy·2026
Same author

Electrochemical and optical biosensors as transformative tools for multiplex detection of influenza viruses.

Archives of microbiology·2026
Same author

Biosensors as transformative tools for multiplex detection of respiratory viral pathogens.

Archives of microbiology·2026
Same author

Functions and mechanisms of exosomal lncRNAs in esophageal cancer.

Discover oncology·2026
Same author

Exosome-mediated crosstalk in rheumatoid arthritis: Pathogenic mediators to next-generation therapeutics.

Clinica chimica acta; international journal of clinical chemistry·2026

Related Experiment Video

Updated: May 5, 2026

Exosomal miRNA Analysis in Non-small Cell Lung Cancer NSCLC Patients' Plasma Through qPCR: A Feasible Liquid Biopsy Tool
08:49

Exosomal miRNA Analysis in Non-small Cell Lung Cancer NSCLC Patients' Plasma Through qPCR: A Feasible Liquid Biopsy Tool

Published on: May 27, 2016

11.3K

Leukemia miRNA electrochemical biosensors.

Mohammad Hassan Sadeghi1, Sohrab Minaei2, Maryam Ashourpour2

  • 1Medical Student, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.

Clinica Chimica Acta; International Journal of Clinical Chemistry
|August 25, 2025
PubMed
Summary

MicroRNAs (miRNAs) are key biomarkers for leukemia, and novel biosensors offer a rapid and accurate method for their detection. This technology aids in early cancer diagnosis and improved patient outcomes.

Keywords:
Electrochemical biosensorsLeukemiamiRNAs

More Related Videos

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening
08:14

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening

Published on: October 26, 2017

15.8K
Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer
08:12

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer

Published on: March 14, 2019

5.6K

Related Experiment Videos

Last Updated: May 5, 2026

Exosomal miRNA Analysis in Non-small Cell Lung Cancer NSCLC Patients' Plasma Through qPCR: A Feasible Liquid Biopsy Tool
08:49

Exosomal miRNA Analysis in Non-small Cell Lung Cancer NSCLC Patients' Plasma Through qPCR: A Feasible Liquid Biopsy Tool

Published on: May 27, 2016

11.3K
MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening
08:14

MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier MSC for Lung Cancer Screening

Published on: October 26, 2017

15.8K
Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer
08:12

Detection of a Circulating MicroRNA Custom Panel in Patients with Metastatic Colorectal Cancer

Published on: March 14, 2019

5.6K

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Biomedical Engineering

Background:

  • MicroRNAs (miRNAs) are non-coding RNAs regulating gene expression, crucial in diseases like cancer.
  • Leukemias are blood cancers characterized by uncontrolled white blood cell growth.
  • Dysregulated miRNA expression correlates with leukemia progression and prognosis, highlighting their role as biomarkers.

Purpose of the Study:

  • To review the design, functionality, and applications of miRNA electrochemical biosensors for leukemia detection.
  • To emphasize the potential of biosensors for early and accurate diagnosis of leukemia.
  • To explore how miRNA identification can improve treatment and patient recovery.

Main Methods:

  • Review of current literature on miRNA biosensors and their application in leukemia.
  • Analysis of biosensor design principles, including electrochemical detection methods.
  • Evaluation of the sensitivity and specificity of miRNA biosensors for cancer biomarkers.

Main Results:

  • Specific miRNAs (e.g., miR-155, miR-181) are implicated in leukemia subtypes and therapy response.
  • miRNA biosensors demonstrate high sensitivity and specificity for detecting cancer-related miRNAs.
  • Electrochemical biosensors offer a rapid, non-invasive, and accurate approach for leukemia diagnosis.

Conclusions:

  • miRNA electrochemical biosensors represent a promising tool for non-invasive leukemia diagnosis.
  • Early detection via miRNA biosensors can significantly impact treatment strategies and patient prognosis.
  • Further development of these biosensors can enhance leukemia management and personalized medicine.