[Possibilities and Limitations of CT-guided Intervention]

Area of Science:

• Pulmonology
• Interventional Radiology
• Oncology

Background:

• CT-guided transthoracic lung biopsy (CT-TTNB) is crucial for diagnosing pulmonary nodules and masses.
• Lung ablation techniques like RFA, MWA, and cryoablation are established minimally invasive therapies for lung tumors.

Purpose of the Study:

• To highlight the diagnostic accuracy and therapeutic value of CT-guided procedures in lung cancer care.
• To emphasize the role of CT-TTNB in obtaining tissue for molecular analysis and personalized therapy.
• To present CT-guided ablation as a treatment option for inoperable lung cancer patients.

Main Methods:

• Utilizing core-needle biopsies for high-quality tissue acquisition in CT-TTNB.
• Employing minimally invasive ablation techniques (RFA, MWA, cryoablation) for targeted tumor destruction.
• Integrating imaging and interventional techniques for enhanced patient safety and outcomes.

Main Results:

• CT-TTNB demonstrates high diagnostic accuracy with 85-97% sensitivity and 85-100% specificity.
• Lung ablation achieves high local tumor control with acceptable complication rates.
• Combined CT-guided puncture and ablation offer precise, low-risk alternatives to invasive procedures.

Conclusions:

• CT-guided transthoracic lung biopsy and ablation are integral to modern lung cancer diagnostics and therapy.
• These CT-guided interventions provide effective patient care for primary and secondary lung tumors.
• The integration of imaging and intervention significantly improves safety and treatment outcomes in lung cancer management.