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Published on: August 5, 2016
Human herpesvirus type 4 combined with Brucella abortus meningitis case report
Jingjing Yang1,2, Feixiang Zhang2, Xiaolong Guo2,3
1Affiliated Baotou Clinical College of Inner Mongolia Medical University, Baotou, Inner Mongolia, 014000, China.
Objective:
To observe and analyse the clinical characteristics, diagnosis and treatment of Human herpesvirus type 4 combined with Brucella abortus meningitis, in order to improve clinicians' understanding of this disease.
Methods:
The clinical data of a patient withHuman herpesvirus type 4 combined with Brucella abortus meningitis diagnosed on 8 January 2024 in Baotou People's Hospital were analysed. Results The case was a middle-aged female patient with the main symptoms of dizziness and numbness and weakness of the limbs. The pathogenic microorganisms were detected as macrogenomic and copy number anomalies by double-homology: Human herpesvirus type 4 was detected as sequence number 13, and the serum Brucella abortus tiger-red plate agglutination test was positive.
Results:
Brucella tube agglutination test: 1:400 ++. Symptoms improved significantly after treatment with doxycycline + rifampicin + cotrimoxazole tablets and prednisone acetate tablets.
Conclusion:
Human herpesvirus type 4 (EBV) combined with Brucella abortus meningitis is a rare infectious encephalitis with a poor prognosis and high recurrence rate. A step therapy strategy of antibiotics combined with glucocorticoids is currently recommended to control acute phase symptoms and reduce the risk of recurrence.
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