Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Differentiation between malignant and non-malignant pleural effusion.

G Mårtensson, K Pettersson, G Thiringer

    European Journal of Respiratory Diseases
    |November 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Midwifery Continuity of Care During Pregnancy, Birth, and the Postpartum Period: A Matched Cohort Study.

    Birth (Berkeley, Calif.)·2024
    Same author

    Lectin-nanoparticle concept for free PSA glycovariant providing superior cancer specificity.

    Clinica chimica acta; international journal of clinical chemistry·2024
    Same author

    A Case Series on Pregnant Patients with Mild Covid-19 Infection and Signs of Severe Placental Insufficiency.

    Case reports in obstetrics and gynecology·2023
    Same author

    INSPIRA: study protocol for a randomized-controlled trial about the effect of spirometry-assisted preoperative inspiratory muscle training on postoperative complications in abdominal surgery.

    Trials·2022
    Same author

    Massive perivillous fibrin deposition of the placenta and pregnancy outcome: A retrospective observational study.

    Placenta·2021
    Same author

    Health-promoting and -impeding aspects of using peer-learning during clinical practice education: A qualitative study.

    Nurse education in practice·2021
    Same journal

    Microbiological studies of tracheostomy site wounds.

    European journal of respiratory diseases·1987
    Same journal

    The effect of a peptide aldehyde reversible inhibitor of elastase on a human leucocyte elastase-induced model of emphysema in the hamster.

    European journal of respiratory diseases·1987
    Same journal

    Procoagulant activities in human alveolar macrophages.

    European journal of respiratory diseases·1987
    Same journal

    Occurrence of breathing problems induced by cold climate in asthmatics--a questionnaire survey.

    European journal of respiratory diseases·1987
    Same journal

    Non-invasive diagnosis of pulmonary hypertension in chronic obstructive pulmonary disease. Comparison of ECG, radiological measurements, echocardiography and myocardial scintigraphy.

    European journal of respiratory diseases·1987
    Same journal

    The effect of cigarette withdrawal on asthmatics who smoke.

    European journal of respiratory diseases·1987
    See all related articles

    Diagnosing malignant pleural effusion requires more than cytology. Thoracoscopy significantly improves detection rates, especially when cytology is negative, aiding in timely patient management.

    Area of Science:

    • Pulmonology
    • Oncology
    • Pathology

    Background:

    • Chronic pleural effusion is a common clinical challenge.
    • Malignant etiologies account for a significant proportion of chronic pleural effusions.
    • Accurate diagnosis is crucial for appropriate patient management and prognosis.

    Purpose of the Study:

    • To evaluate the diagnostic performance of various methods for identifying malignant pleural effusion.
    • To assess the predictive value of clinical and fluid characteristics for malignancy.
    • To determine the utility of thoracoscopy in cases with negative pleural fluid cytology.

    Main Methods:

    • Prospective study of 334 patients with chronic pleural effusion.
    • Analysis of pleural fluid cytology and cell atypia.

    Related Experiment Videos

  • Evaluation of thoracoscopy sensitivity.
  • Statistical analysis including logistic regression for predictive variable assessment.

    • Main Results:

    • Malignant etiology was found in 47% of patients.
    • Pleural fluid cytology sensitivity was 43%.
    • Thoracoscopy sensitivity was 80%, identifying malignancy in 37/47 patients with negative cytology.
    • Bloody fluid indicated malignancy; >30% eosinophils suggested a non-malignant cause.
    • Logistic regression model achieved 79% discrimination between malignant and non-malignant etiologies.

    Conclusions:

    • Cytology alone has limited sensitivity for diagnosing malignant pleural effusion.
    • Thoracoscopy is a valuable tool for detecting malignancy when cytology is inconclusive.
    • Clinical and fluid characteristics, analyzed statistically, can aid in predicting malignant etiology.
    • Diagnostic strategy should incorporate these findings to guide further invasive procedures and follow-up intensity.