Related Experiment Video
Updated: Jul 13, 2026

21:16
An In Vitro Skin Irritation Test SIT using the EpiDerm Reconstructed Human Epidermal RHE Model
Published on: July 13, 2009
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Caprylyl Glycol, a Trending and Highly Relevant Sensitiser in Cosmetics That Needs to be Patch Tested Separately
Silada Kanokrungsee1,2, Ella Dendooven1, Olivier Aerts1
1Department of Dermatology, University Hospital Antwerp (UZA) and Research Group Immunology, INFLA-MED Centre of Excellence, University of Antwerp, Antwerp, Belgium.
Contact Dermatitis
|August 26, 2025
Abstract
No abstract available in PubMed .
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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...

