Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

5.2K
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
5.2K
Extraction: Advanced Methods00:56

Extraction: Advanced Methods

524
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
524
Methods of Classification and Identification01:28

Methods of Classification and Identification

181
Bacterial identification relies on a diverse array of techniques to classify and understand microorganisms, each tailored to uncover specific characteristics. Traditional morphological approaches, while still valuable, are limited for closely related or structurally simple organisms. Modern methods integrate biochemical, serological, genetic, and advanced molecular tools to achieve greater accuracy.Morphological and Biochemical TechniquesMorphological characteristics, such as cell shape and...
181

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chronic ethanol self-administration alters dopamine in the caudate nucleus and putamen of rhesus macaques in a sex-dependent manner.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2026
Same author

Chronic alcohol consumption disrupts the gut microbial and metabolic landscapes.

Frontiers in microbiology·2026
Same author

Spaceflight and the rodent skeleton: A perspective.

Bone reports·2026
Same author

Altered molecular signaling pathways in the hippocampus of rhesus monkeys following chronic alcohol use.

Scientific reports·2026
Same author

Nanopore-based sequencing of active DNA replication reveals key principles of metazoan replication dynamics.

Science advances·2026
Same author

Cross-Species evidence for hippocampal CACNA1C as a therapeutic target for alcohol use disorder.

Translational psychiatry·2026
See all related articles

Related Experiment Video

Updated: Sep 8, 2025

Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
13:44

Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns

Published on: August 30, 2013

43.0K

Image processing approach provides robust feature extraction for classification with small sample sizes.

Alibek Zhakubayev1, Thomas L Andersen2,3, Annie Vesterby3

  • 1Department of Computer Science, Baylor University Waco, Texas, USA.

Proceedings of the 2023 7Th International Conference on Information System and Data Mining : Atlanta, GA, United States, May 10-12, 202. International Conference on Information System and Data Mining (7Th : 2023 : Atlanta, Ga.)
|August 26, 2025
PubMed
Summary
This summary is machine-generated.

Chronic alcohol consumption impacts bone health. Novel image analysis techniques reveal subtle, detectable changes in bone architecture across species, aiding skeletal health research.

Keywords:
alcoholbonemachine learningmicrocomputed tomographyrhesus macaque

More Related Videos

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.6K
Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
04:48

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography

Published on: November 30, 2022

2.9K

Related Experiment Videos

Last Updated: Sep 8, 2025

Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
13:44

Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns

Published on: August 30, 2013

43.0K
Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

7.6K
Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
04:48

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography

Published on: November 30, 2022

2.9K

Area of Science:

  • Orthopedics and Imaging Analysis
  • Biomedical Engineering
  • Anthropology

Background:

  • Chronic alcohol consumption negatively affects skeletal health and bone architecture.
  • Medical imaging offers potential for machine learning-based analysis of alcohol's skeletal effects.
  • Small sample sizes in medical imaging studies hinder traditional machine learning approaches.

Purpose of the Study:

  • To develop a novel image feature extraction technique suitable for small datasets.
  • To analyze the impact of intrinsic (age, sex) and extrinsic (alcohol consumption) factors on bone architecture.
  • To assess the generalizability of the developed technique across species.

Main Methods:

  • Developed a novel image feature extraction technique for small image datasets.
  • Applied the technique to microcomputed tomography (micro-CT) images of human and non-human primate bone samples.
  • Trained machine learning models to classify features related to sex and alcohol consumption patterns.

Main Results:

  • Achieved high performance in distinguishing sex-based bone differences (72% in macaques, 65.5% in humans).
  • Successfully differentiated between drinking and non-drinking individuals in both macaques (68%) and humans (65%).
  • Demonstrated the technique's ability to capture generalizable biological features across species.

Conclusions:

  • The novel image processing approach can detect subtle effects of alcohol consumption on bone architecture.
  • The developed technique is effective even with small image datasets, showing cross-species applicability.
  • Findings highlight the potential of medical imaging for understanding alcohol's impact on skeletal health.