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Ambulatory Versus Inpatient Total Laparoscopic Hysterectomy in Trans Men: A Randomised Controlled Non-Inferiority
Bo Verberckmoes1,2, Steffi van Wessel1, Tjalina Hamerlynck1,3
1Women's Clinic, Ghent University Hospital, Ghent, Belgium.
BJOG : an International Journal of Obstetrics and Gynaecology
|August 26, 2025
Summary
Ambulatory total laparoscopic hysterectomy in trans men is non-inferior to inpatient surgery regarding patient satisfaction with hospital stay. This approach demonstrates comparable recovery and lower complication rates, supporting its safe use.
Area of Science:
- Surgical innovation in transgender healthcare.
- Comparative effectiveness of surgical procedures.
Background:
- Hysterectomy is a common procedure for transgender men.
- Assessing the safety and efficacy of ambulatory surgery is crucial for patient outcomes.
Purpose of the Study:
- To determine if ambulatory total laparoscopic hysterectomy is non-inferior to inpatient surgery for transgender men.
- To evaluate patient satisfaction with length of stay and other key outcomes.
Main Methods:
- Single-center non-inferiority randomized controlled trial.
- Transgender men undergoing total laparoscopic hysterectomy were randomized to ambulatory or inpatient care.
- Primary outcome: patient satisfaction with length of stay; Secondary outcomes: pain, analgesic use, recovery, mood, complications, readmission.
Main Results:
- Ambulatory hysterectomy was non-inferior to inpatient surgery for patient satisfaction with length of stay.
- The ambulatory group reported lower pain scores but higher moderate analgesic use.
- Readmission and complication rates were higher in the inpatient group.
Conclusions:
- Ambulatory total laparoscopic hysterectomy is a safe and effective alternative to inpatient surgery for transgender men.
- Patient satisfaction and recovery quality are comparable, with potential benefits in reduced complications.

