[Glycoside poisoning in experimental heart failure and its drug correction]

It has been demonstrated in experiments on 420 rats that antiadrenergic, antihistamine, antihypoxic, anabolic, antiarrhythmic and diuretic agents have different effects on the cardiotoxicity of strophanthine K for intact animals and in experimental heart insufficiency of different genesis. The pharmacological analysis revealed some risk factors capable of provoking glycoside intoxication in circulatory failure. Approaches to the goal-oriented drug correction of the risk factors are proposed.