[Long-term study of endometrial cell sampling and cytologic evaluation with special reference to Prevical and Curity]

The special anatomic approach and difficult cell collecting from all parts of the corpus uteri have so far prevented the development of an ideal instrument for an early detection of endometrial adenocarcinoma. During the past 9 years we examined several methods; this is a report of a long-term study on 2,500 smears with Prevical and 320 with the Isaacs endometrial cell sampler. In particular, the difficulties concerning the highly differentiated carcinoma and all precancerous abnormalities are discussed, and the increasing number of endometrial carcinomas in comparison with those of the cervix uteri are confirmed. In the near future the control of all patients with high risk is recommended, beginning with the age of 40-45. A further aim is to solve cytomorphological and instrumental problems with regard to screening all precancerous stages without exception.