Related Experiment Video
Updated: Sep 10, 2025
07:34
Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound 30/45MHZ System
Published on: May 5, 2018
11.8K
Risk Factors and Temporal Trends of Maternal Heart Failure: A Population-Based Study Over 2 Decades
Clara Kihlborg1, Jonas Faxén2, Maria Sennström3
1Medical Programme, Karolinska Institutet, Stockholm, Sweden.
JACC. Heart Failure
|August 26, 2025
Summary
Maternal heart failure (HF) incidence rose 66% in Sweden over 20 years, with half of cases linked to cardiac conditions. While risk factors play a role, they don't fully explain the trend.
Area of Science:
- Cardiology
- Maternal Health
- Public Health
Background:
- Maternal heart failure (HF) is a growing concern globally, with unclear trends in Sweden.
- The contribution of evolving maternal risk factors and associated cardiac conditions to HF incidence is not well understood.
Purpose of the Study:
- To determine the annual incidence of maternal HF in Sweden from 2000-2019.
- To identify associated cardiac conditions, risk factors, and assess the impact of risk factor changes on HF trends.
Main Methods:
- A national cohort study analyzed 2,078,384 deliveries using Swedish Medical Birth Register data (2000-2019).
- Maternal HF cases were identified via linkage with national patient and mortality registers.
- Multivariable logistic regression analyzed risk factors and incidence rates stratified by onset and cardiac disease status.
Main Results:
- Maternal HF incidence increased by 66% over two decades, reaching 0.34 cases per 1,000 deliveries.
- Approximately 50% of maternal HF cases had associated cardiac disease.
- Prepregnancy comorbidities and pregnancy complications were identified risk factors; changes in prevalence partially explained the rising incidence.
Conclusions:
- The increasing incidence of maternal HF in Sweden presents a significant clinical challenge.
- The high rate of associated cardiac disease necessitates enhanced awareness and management strategies for affected women.
More Related Videos
08:28Analysis of Congenital Heart Defects in Mouse Embryos Using Qualitative and Quantitative Histological Methods
Published on: March 10, 2020
7.0K
05:16Cutoff Value of Phase Angle by Bioelectrical Impedance Analysis at Admission as a Prognostic Factor in Patients with Acute Heart Failure
Published on: June 10, 2025
214
Related Concept Videos
01:27Heart Failure I: Introduction
54
Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
54
01:17Pathophysiology of Heart Failure
1.8K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.8K
01:29Heart Failure II: Pathophysiology
38
Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
38
01:20Mitral Regurgitation I: Introduction
55
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
55
01:30Heart Failure IV: Classification and Diagnostic Evaluation
32
Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
32
01:30Heart Failure VII: Nursing Interventions
139
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
139